Eye Disease
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Entropion is primarily an inherited condition. The upper or lower eyelid turns inward, rubbing against the eye due to an excess of eyelid tissue, or a small eye, or both. Most affected dogs exhibit eye irritation.  Frequently, corneal scratches can result.  Occasionally the condition is self-correcting as the puppy grows, but in the vast majority of affect dogs, surgery is necessary to turn the eyelid away from the surface of the eye.

What is Entropion?
Canine Eyelid Diseases
Eye Problems In Dogs, Don't Be Fooled

PRA, a form of hereditary blindness, was once a serious problem in Irish setters. A DNA test, however, is now available through Optigen to determine which Irish setters are PRA carriers and which are not. In Irish setters, PRA is a simple recessive and can therefore be eliminated from breeding programs by breeding known non-carriers to known non-carriers.

Optigen PRA Description & Testing Info
Optigen Testing Costs
Optigen Test Request Printable Form
Optigen Test Request Online
OFA ISGR Registration Form
OFA Irish Setter Genetic Registry GTA Application
CERF Website
Irish Setter DNA Registry
American College of Veterinary Opthalmologists
Human vs. Canine Vision

In 2011, a recessive mutation that is associated with the development of Late Onset PRA was discovered in the Irish Setter.  Currently, the only DNA test availabe is located in the United Kingdom.  Test kits may be ordered for the U.K. for testing the Irish Setter in the United States.  Late onset PRA can present itself in dogs as young as 4 years old and as old as 10 years old. 

Animal Health Trust - History & Description
Current Research - Irish Setter Club of America
Jerold S Bell, DVM Article
Order Test Kits
OFA Submit Test Results
OFA DNA Testing for rcd4 PRA
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